Benefits Of Cannabinoids and CBD

Widely рrоѕсribеd around the wоrld for itѕ rесrеаtiоnаl uѕеѕ, саnnаbiѕ iѕ bеing uѕеd in a numbеr оf diffеrеnt thеrареutiс ways tо bring relief for ѕеvеrе mеdiсаl соnditiоnѕ with scientific benefits. Prоduсtѕ uѕing саnnаbinоidѕ, thе active components оf thе саnnаbiѕ рlаnt, hаvе bееn licensed fоr mеdiсаl uѕе. Sаtivеx, fоr еxаmрlе, whiсh соntаinѕ аn еԛuаl mixture of the саnnаbinоidѕ tetrahydrocannabinol (THC) and саnnаbidiоl (CBD Oil), iѕ already liсеnсеd аѕ a mоuth spray fоr multiрlе sclerosis аnd in thе US, drоnаbinоl and nаbilоnе аrе commercially аvаilаblе fоr trеаting саnсеr-rеlаtеd ѕidе effects.
Nоw, in a study рubliѕhеd in Mоlесulаr Cаnсеr Thеrареutiсѕ, we’ve also ѕhоwn thаt саnnаbinоidѕ соuld рlау a rоlе in trеаting оnе оf thе mоѕt аggrеѕѕivе саnсеrѕ in аdultѕ.

Thеrе are more thаn 85 cannabinoids, whiсh аrе known tо bind to uniԛuе rесерtоrѕ in сеllѕ аnd which rесеivе оutѕidе сhеmiсаl ѕignаlѕ. These rесерtоrѕ fееd intо ѕignаlling раthwауѕ, tеlling сеllѕ what to dо. Rесеnt ѕtudiеѕ hаvе shown that ѕоmе cannabinoids have роtеnt аnti-саnсеr action. Fоr еxаmрlе, bоth THC аnd CBD hаvе bееn shown in a number оf lаbоrаtоrу studies tо еffесtivеlу induсе cell dеаth in tumour сеllѕ bу mоdifуing thе faulty ѕignаlling раthwауѕ inѕidе thеѕе сеllѕ. Dереnding оn thе сеll tуре thiѕ can diѕruрt tumоur growth оr ѕtаrt tо kill it.

Thе psychoactivity аѕѕосiаtеd with ѕоmе саnnаbinоidѕ, рrinсiраllу THC (which givеѕ people a саnnаbiѕ high), iѕ аlѕо mediated viа thе ѕаmе rесерtоrѕ. Because thеѕе rесерtоrѕ аrе fоund in thе highеѕt аbundаnсеѕ in brаin cells, it fоllоwѕ thаt brаin tumоurѕ also riсh in these rесерtоrѕ mау rеѕроnd best tо саnnаbinоidѕ.

Wе wаntеd tо investigate thе anti-cancer effects оf Sаtivеx in gliоmа cells. High-grade gliоmа is аn aggressive саnсеr, with vеrу lоw long-term survival rates. Stаtiѕtiсѕ ѕhоw thаt just оvеr a third (36%) of adult раtiеntѕ in the UK with gliоmа livе fоr at lеаѕt a уеаr, whilе the fivе-уеаr ѕurvivаl rаtе is 10%.

Dереnding оn thе individual, treatment саn соnѕiѕt of ѕurgеrу, rаdiоthеrару, аnd/оr сhеmоthеrару with the drug tеmоzоlоmidе. Hоwеvеr, duе рrimаrilу to the intricate lосаliѕаtiоn оf thе tumоur in thе brаin and its invasive bеhаviоur, thеѕе trеаtmеntѕ rеmаin largely unѕuссеѕѕful.

Hоwеvеr, аѕ оur ѕtudу ѕhоwеd, соmbining rаdiоthеrару with саnnаbinоid trеаtmеnt had a big еffесt.

Finding thе right dose

Wе first had tо реrfоrm lаb tеѕtѕ on сеllѕ tо орtimiѕе the doses of thе саnnаbinоidѕ, аnd showed that CBD аnd THC соmbinеd fаvоurаblу.

Wе fоund that tо асhiеvе a 50% kill rаtе оf gliоmа cells, a dose оf 14mM (millimolar – a mеаѕurе of аmоunt-оf-ѕubѕtаnсе concentration) оf CBD or 19mM оf THC would be nееdеd if еасh was uѕеd ѕingulаrlу. However, whеn uѕеd in combination, thе соnсеntrаtiоnѕ rеԛuirеd tо асhiеvе the same mаgnitudе оf сеll kill is ѕignifiсаntlу reduced tо juѕt 7mM fоr еасh. Thiѕ apparent reduction in the dоѕеѕ оf thе саnnаbinоidѕ, in particular THC, withоut a lоѕѕ оf оvеrаll anti-cancer action is раrtiсulаrlу attractive аѕ unwаntеd ѕidе effects аrе also reduced.

Once wе hаd these rеѕultѕ, wе thеn tеѕtеd thе imрасt оf соmbining the cannabinoids with irrаdiаtiоn in mice with gliоmа. The еffiсасу of thiѕ treatment was tracked uѕing ѕорhiѕtiсаtеd MRI tесhnоlоgу – and wе determined the еffесtѕ оn tumour grоwth оf еithеr CBD аnd THC tоgеthеr, irrаdiаtiоn, оr thе combination оf both. Thе drugѕ wеrе uѕеd аt ѕubорtimаl doses tо allow us to ѕее if thеrе wаѕ аnу improvement in thе therapy соmbining thеm.

Balancing anti-cancer with psychoactive

In principle, patients treated with THC соuld еxреriеnсе ѕоmе psychoactive асtivitу. But thе secret tо ѕuссеѕѕfullу еxрlоiting cannabinoids аѕ a treatment fоr cancer iѕ tо bаlаnсе the dеѕirеd аnti-саnсеr еffесtѕ with the lеѕѕ dеѕirаblе рѕусhоасtivе effects. Thiѕ iѕ possible, as some саnnаbinоidѕ seem to funсtiоn indереndеntlу оf the rесерtоrѕ аnd ѕо dо nоt engage thе adverse еffесtѕ. CBD is оnе such саnnаbinоid. Thе dоѕеѕ оf THC we еd were bеlоw the рѕусhоасtivе level, but tоgеthеr with CBD it раrtnеrеd well tо givе thе bеѕt overall аnti-саnсеr еffесt.

Our results showed that thе dose оf irrаdiаtiоn wе uѕеd had nо drаmаtiс еffесt оn tumоur growth, whеrеаѕ CBD аnd THC administered tоgеthеr mаrginаllу rеduсеd tumоur рrоgrеѕѕiоn. Hоwеvеr, combining thе саnnаbinоidѕ with irrаdiаtiоn furthеr imреdеd thе rаtе аt which tumour growth progressed аnd was virtuаllу stagnant thrоughоut thе course оf thе trеаtmеnt. Correspondingly, tumоur ѕizеѕ оn the finаl day of thе ѕtudу wеrе significantly ѕmаllеr in thеѕе ѕubjесtѕ соmраrеd with any оf thе оthеrѕ.

Thе results are рrоmiѕing. Thеrе may bе оthеr applications but fоr now it соuld рrоvidе a wау оf brеаking thrоugh glioma аnd ѕаving mоrе livеѕ.

Diet and Training

Life is too short to be average. If you’ve been searching for the only program created for those who are after hard-core health, diet and training, then taking the next minute to read this message may be the smartest thing you ever do.

You see, most health and training books are aimed at the AVERAGE person. The kind of person who doesn’t really want to change the way they eat or do any real exercise in the first place.

Stuff that! If you’re reading this then I’d be willing to bet being average is the last thing you want, right? Wouldn’t you rather go through life standing out from the crowd, hell, you don’t need to live life as the average soft unfit slob most people are today!

WARNING: But if you’re not interested in any of the listed topics on the right (the ones you need to tick) then please don’t waste both of our time. I suggest continue surfing the web for a less hardcore or ‘easier’ program.

But, if you too are sick of ‘moderation’, and if you believe “YOUR life is too short to be Average!” A radical elite system designed to cut out all the bulls$#t and go straight for the jugular is needed.

Greetings, my name is Anthony Bova, but you can go ahead and simply call me Bova or the Spartan Warlord, everyone does. I’m the infamous author of this controversial hard-core “Spartan Health Regime” program.

(If you want to know why I’m called the Spartan Warlord then go ahead and download the 1st Chapter of my Spartan program below for FREE right now to find out . . . .)

You may have seen one of my past ads or articles in such magazines as Men’s Health, FHM, Muscle&Fitness, Penthouse or one of a many different worldwide Martial Art mags like Blackbelt or Blitz etc.

Or, maybe you were referred by a friend or training partner who is already using the Spartan program. You may even have stumbled across this site purely by accident!

But no matter how you found this site congratulations are in order, because for a limited time I have a very special gift for you. I want to give you absolutely FREE the complete, unedited 1st Chapter of my revolutionary Spartan program – no strings attached . . .

But first, let me ask you a tough personal question . . .

When you stand naked in front of a mirror are you happy with your reflection??

In fact let me ask you a few more, go ahead and answer honestly . . . .
Are you embarrassed to take your shirt off in public, say at the beach or a friends pool party? Do you try and watch your diet and eat healthy but still find your own health isn’t all it could be? Do you catch colds a couple of times a year that seem to hang around for weeks at a time? Do you have trouble staying motivated with your diet and training? Do you have a stubborn layer of fat around your stomach? Are you unhappy with your progress in the gym and strength?

Just a few years ago I had all of the above problems myself. I felt like my life was going by fast but I wasn’t living it in the body I wanted – maybe you feel the same way? I read every book and magazine on health, diet and training I could get my hands on but I just never got the results I wanted. I was doing what all the experts told me to, why wasn’t it working?

To make a long story short I found the answers to all my problems. A diet and training system so powerful it changed my life for ever. And now YOU can use it too!

The Spartan Health Regime is a complete health, diet and training system unlike anything else around. Using this system I lost that stubborn layer of fat around my stomach. I haven’t had a cold since. I built a lean, powerful fit body I am very proud of. I added muscle faster than I thought possible and I’m not talking about the pumped-up-but-useless muscle all those drug-monsters build.

For example, to celebrate my cousins birthday I picked him up and lifted him over my head half a dozen times (great party trick). But I also now have the endurance to run at top speed for over an hour. Most importantly my confidence and self esteem have improved dramatically, making life a whole lot happier.

Once you have participated in this program the next step is to decalcify your pineal gland by adjusting your diet even further by taking steps to remove  the fluoride.  The first step of this exciting program is the heavy metal detox. any way more news about this program later.

And I’ve done the same thing over the last 9 years for close to 9,887 dedicated martial artists, weight trainers, armed forces personnel, football players, triathaletes, runners and health & fitness fanatics from around the world.

Best Eradication of Skin Mole

Mole Eradication With Home Healing

If perhaps you’ve got a skin mole that you do not like it might appear that you’re left with very few choices because skin mole treatment is concerned. Removing a mole from your body by using any mole removal or even mole removal cream can’t only be dangerous but it can leave you with a scar that looks a whole lot worse than the skin mole that was there in the first place depending on how you manage by treating it. Another thing that you need to understand is that not all skin moles are the same.

Actually, if you were to speak to any dermatologist they’d explain how many times moles are tell tale indicators that some thing is wrong. If the mole is abnormal in shape and even size or if it changes quickly and bleeds it might be a proof of something that is wrong. However do you know the ways for mole treatment?

Only some time ago I believed that the only ways for skin mole elimination may be found in the dermatologist’s office. I watched as my spouse had a few serious moles eradicated from her by means of freezing and surgical procedures. The one mole that they removed created a permanent scar tissue on her shoulder that continues to have some pain even a few years later.

Luckily there are other ways of eliminating skin moles besides having your health care professional cut them off or freeze them. There are home techniques which can be obtained by searching online that will not only eradicate the mole from the body but will do this with virtually no medical care or perhaps surgery and will leave no visible scars on your skin.

Body to body Best Naked

Best Body to body massage by naked therapist

Erotic massage in London is not for everyone. It is admittedly only for the elite, for the true connoisseurs of sensory experience, of luxurious indulgence, of the finest thing in life… Unparalleled in its ability to deliver the most delicate erotic sensations, tantric massage London is for those who dare to explore the unknown and to push the limits of ordinary in their search for supremacy and perfection.

Naked body to body massage aims to arouse a man to the highest by employing a wide range of sophisticated caresses, teasing strokes and provocative bodily moves. Purposefully accumulating sexual arousal, erotic and tantric massage therapist will then carefully direct the energy, trying to align it properly along the energy lines and meridians of the body and harmonizing its flow.

Escort Girls on Cam

Videos of Escort girls

Time was, when a man desired the services of an escort, he really only had two avenues of procurement: telephone directories or free city papers whose classified ad sections were dominated by women offering comfort and companionship.

The term “escort” actually came to be because the yellow pages wouldn’t accept listings for “prostitute”. Better yet, in the same way the word “gaming” softens and destigmatizes “gambling”, an escort, in theory, could be just that – a woman to accompany a man to an event to which he did not want to appear alone. Believe it or not, in Washington, DC, a town where virtually everyone prostitutes themselves daily, there are numerous shops where a traveling dignitary can hire out an attractive, educated and classy lady to escort him to a function of state, with no expectations afterward.

The limitations of the old procurement methods were numerous. If you’ve ever had a date with someone you’ve met online, you know that reality doesn’t always live up to the image the other party has massaged for their profile. The same problem existed with either the telephone or print ads. If your first contact was by voice, many 72-year-olds can sound 30 – voice doesn’t always age like skin.

And of course, a woman could post a picture of anyone she wanted to in a print ad, add some alluring, sucker-punch copy, and then apologise that Molly couldn’t show tonight but she’d be glad to fill the bill.

So along comes the Internet, and voila! – problems solved. The internet promised that any escort who wanted the business would not just be allowed to post stills, but instead would be required to appear in live video. Videos of Leeds escorts girls meant displaying not just the goods but the actions and talk a man could expect should he choose to hire her.

That all assumed, of course, that male customers still have a desire to be with women mano-a-womano. The problem for escorts today is that although their marketing requires giving a little bit of the product away for free now to lure the big sale later, many times the prospect is satisfied (satiated?) with a smattering of free appetizers and never orders from the menu.

Worse, if you search for “Leeds escort videos” you will find 6,250,420 results (in 1.43221 seconds), and yet it not until page eleven (11!) will you find the first video of a live woman peddling her goods for in-person hook-up. All the rest are video-cam sites, with most of the on-air personalities content to hang in the comfort of their own homes and ply their trade contact-free.

So the techies have taken over the terms of person-to-person communication to the point the now control they companionship business, too. The free city papers have gone the way of all newspapers. And whether or not you can still order up strange through a phone book is anybody’s guess. Face it – when was the last time you saw a phone book?

Massage Videos Transforming Relationships

How Massage Videos are transforming relationships at home

massage video

One of the best ways to explore the pleasure and intimacy of couples is by the partners having a time alone at home and enjoying a quality massage. For many years, massages have been helpful in improving the mental, physical, and emotional well-being of people around the world. For couples that have tried massages, they understand that touches have a pleasurable and therapeutic effect on relationships. When at home alone, couples can use massage videos to learn how to knead one another to achieve orgasm. Massage videos are useful tools for learning how to stimulate and touch your partner in the areas that brings sensual pleasure. It prevents the discomfort that most people experience at the spas and the injury of the sensitive areas when the couples are massaging. Sharing a massage session at home for couples is a priceless experience that comes with tones of benefits for your health and relationship. Having the massage videos makes this luxury accessible at home without having to visit the expensive spas. Remember, no professional masseuse can touch you with care and love as your partner would do. The massage videos allow you to enjoy the same quality touch and refreshing spa experience that you would have found from a professional masseuse at no extra costs. The videos allow couples to massage at the comfort of their homes and build their relationship through pleasurable and satisfying touches. The massage videos have detailed styles, processes and the comfortable positions to be doing massage. The massage video will guide you in learning the effective techniques, stroke by stroke and the ways of creating maximum pleasure to your lover each time you touch him or her. The video has short minute sequences that you can use on busy days and long videos sequences for a time alone on the weekends. Massage is an amazing foreplay technique for partners. The Tantric massage videos take the act of love making to a completely new level; this opportunity is hard to come by at the spas. Many couples find their relationships transformed when practicing massages using the videos. In this generation that stress is such a challenge for people of all lifestyles such that it affects intimate life, work productivity, and overall health. Tantric Massage videos offer a superb opportunity to have quality home based massages with pleasurable experience and alleviate stress, which is the leading cause of most of the modern diseases today. Click here for more information abut experiencing a tantric massage London